cas 13463-67-7 manufacturer

JECFA previously assessed titanium dioxide at its 13th meeting, at which time the expert committee assigned a “not specified” ADI for the additive due to an absence of significant absorption and a lack of toxicological effects in the available experimental animal and human studies. Since its original evaluation by JECFA, titanium dioxide has become a public point of contention, with its ban being introduced (and then subsequently withdrawn) in California legislation in 2023, a legal battle playing out in the EU over the additive’s ban and classification as a carcinogen in 2022, and the European Food Safety Authority (EFSA) calling titanium dioxide unsafe. However, supporters of titanium dioxide say that claims about its dangers are founded in unreliable studies, and some recent research has supported its safety as a food additive.

...
  • While the FDA maintains that the regulated use of titanium dioxide is safe, the European Food Safety Authority and some other experts warn of potential, serious health risks.

  • The determination of sulfate in various matrices is a critical task for environmental monitoring, industrial process control, and quality assurance in chemical production. When present in high concentrations, sulfates can pose health risks and impact the ecosystem. However, the analytical challenge often lies not just in detecting the presence of sulfates but also in accurately quantifying them, especially when they are to be determined as titanium dioxide (TiO2). This article delves into the methodologies used to determine sulfate as TiO2, highlighting the complexities and nuances involved in such an analysis.